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Vanadium and Vanadyl Sulfate for Diabetes and
Page last edited by Earl,
mineral which works like insulin to increase the amount of glucose and
amino acids driven into the muscle. Vanadyl Sulfate is a
compound of Vanadium, Sulfur, and Oxygen.
Mineral element found naturally in some food and
body that helps to
balance blood sugar levels and aids in the release of energy.
Food sources rich in Vanadium
Studies have shown both positive and negative health effects of
Vanadium and Vanadyl
Example of positive
sulfate improves hepatic and
muscle insulin sensitivity in type 2 diabetes
Clin Endocrinol Metab. 2001 Mar;86(3):1410-7.
According to a study performed by the University
Texas Health Science Center, San Antonio, Texas in 2001, Vanadyl
Sulfate was shown to
reduce hyperglycemia, improved liver and muscle insulin
significantly improved glycemic control
in a small study of (11) people with type 2 diabetes. Another
benefit was that
Sulfate reduced cholesterol levels (including LDL cholesterol)
Abstract of the study:
of Texas Health Science Center, San Antonio, Texas 78284, USA.
sulfate (VOSO(4)) is an oxidative form of vanadium that in vitro and in
animal models of diabetes has been shown to reduce hyperglycemia and
insulin resistance. Small clinical studies of 2- to 4-week duration in
type 2 diabetes (T2DM) have led to inconsistent results. To define its
efficacy and mechanism of action, 11 type 2 diabetic patients were
treated with VOSO(4) at a higher dose (150 mg/day) and for a longer
period of time (6 weeks) than in previous studies. Before and after
treatment we measured insulin secretion during an oral glucose
tolerance test, and endogenous glucose production (EGP) and whole body
insulin-mediated glucose disposal using the euglycemic insulin clamp
technique combined [3-(3)H]glucose infusion. Treatment significantly
improved glycemic control: fasting plasma glucose (FPG) decreased from
194 +/- 16 to 155 +/- 15 mg/dL, hemoglobin A(1c) decreased from 8.1 +/-
0.4 to 7.6 +/- 0.4%, and fructosamine decreased from 348 +/- 26 to 293
+/- 12 micromol/L (all P < 0.01) without any change in body
Diabetics had an increased rate of EGP compared with nondiabetic
controls (4.1 +/- 0.2 vs. 2.7 +/- 0.2 mg/kg lean body mass.min;
0.001), which was closely correlated with FPG (r = 0.56; P<
Vanadyl sulfate reduced EGP by about 20% (P< 0.01), and the
in EGP was correlated with the reduction in FPG (r = 0.60; P<
Vanadyl sulfate also caused a modest increase in insulin-mediated
glucose disposal (from 4.3 +/- 0.4 to 5.1 +/- 0.6 mg/kg lean body mass
x min; P< 0.03), although the improvement in insulin sensitivity
not correlate with the decline in FPG after treatment (r = -0.16; P =
NS). Vanadyl sulfate treatment lowered the plasma total cholesterol
(223 +/- 14 vs. 202 +/- 16 mg/dL; P < 0.01) and low density
lipoprotein cholesterol (141 +/- 14 vs. 129 +/- 14 mg/dL; P <
whereas 24-h ambulatory blood pressure was unaltered. We conclude that
VOSO(4) at maximal tolerated doses for 6 weeks improves hepatic and
muscle insulin sensitivity in T2DM. The glucose-lowering effect of
VOSO(4) correlated well with the reduction in EGP, but not with
insulin-mediated glucose disposal, suggesting that liver, rather than
muscle, is the primary target of VOSO(4) action at therapeutic doses in
Example of negative
Effect of Vanadium on Insulin Sensitivity in Patients
with Impaired Glucose Tolerance
Source: Ann Nutr Metab. 2008 Nov 22;53(3):195-198
This study showed that Vanadyl
Sulfate caused triglyceride levels to go up
when given to 14 overweight
and obese people with impaired glucose tolerance. Triglycerides are a
kind of blood fat. Triglyceride levels
going up is undesirable,
since high triglycerides alone can increase your risk of
cardiovascular disease. [According to Mayo
Clinic.] The 14 people in this study
did not see
any improvement in insulin sensitivity either. This small
study suggests that Vanadium is not a good choice for overweight or
obese people that already have impaired glucose tolerance.
Abstract of the study:
O, González-Ortiz M, Martínez-Abundis E, López-Madrueño JF,
Research Unit in Clinical Epidemiology, Medical Unit of High Specialty,
West National Medical Center, Mexican Institute of Social Security,
Impaired glucose tolerance (IGT) is considered a risk factor for
developing type 2 diabetes mellitus (T2DM) and is associated with
insulin resistance. Vanadium seems to block protein tyrosine
phosphatase with the consequent increment in insulin sensitivity (INS)
in T2DM patients, but this effect has not been studied in IGT patients.
The aim of this study was to evaluate the effect of vanadium on INS in
IGT patients. Methods: A randomized, double-blind, placebo-controlled
clinical trial was carried out in 14 overweight/obese patients with
IGT. Intervention consisted of vanadyl sulfate (VS, 50 mg p.o. twice
daily) or placebo for 4 weeks. Before and after the intervention, a
metabolic profile was performed and INS was assessed using the
euglycemic-hyperinsulinemic clamp technique. Mann-Whitney U and
Wilcoxon rank tests were used for statistical analyses. Results: There
were no significant differences in basal characteristics between
groups. VS did not affect INS [2.7 +/- 0.8 vs. 2.9 +/- 0.9 mg/(kg/min),
p = 0.735] but increased triglyceride levels (1.35 +/- 0.61 vs. 1.70
+/- 0.46 mmol/l, p = 0.018). Conclusions: VS administration in IGT
patients increased triglyceride concentrations without changes in INS.
Copyright © 2008 S. Karger AG, Basel.
In the future, stem cells may be used to help patients
with type 1 diabetes gain insulin independence. Details are in the
Monday, September 4, 2006 at 19:42
I worked for a Holistic Doctor for 2 1/2 years . He had me on Vanadium
from a company called nutra west . I was taking 3 to 4 pills a day . It
really kept my sugar from getting high . Sense he died , I can't find a
Doctor that sales this . I have tried other products , But they don't
seem to work as good .
Friday, February 08, 2008 7:10 PM
I am taking 5000 mcg daily ( 1capsule) of vanadyl
sulfate to help control my blood sugar. What would be your recommended
dosage? I am type two diabetic. Your input would be most appreciated.
- Friday, February 22, 2008 at 09:34
I used to purchase Vanadyl sulfate from Olympian Labs
but they no longer carry it. Where can I purchase some now? thank you
Saturday, March 15, 2008 at 11:29
world carries vanadyl
sulfate in there catalog
or order on line
September 8, 2008 at 10:12 PM
You can find vanadyl
or vanadium from Puritan
Larry - Monday,
March 16, 2009 at 02:12 AM
You can find Vanadium
from Swanson for about $3.49 for 60 caplets, they even put it in some
of their multiple vitimins.
I decided to let visitors add links to online stores that sell
Vanadyl Sulfate or Vanadium. I went back through the comments
above and added links to the sources that visitors found. If
know of more sources where you can buy these products, you may add them
here in the comments.
James - Wednesday,
May 20, 2009 at 8:30 PM
Vanadyl Sulfate 5000 mcg (micro grams), 180 capsules, can be purchased
from Super Supplements for approximately $9.
Jules - Thursday,
July 9, 2009 at 1:20 PM
Many of you have already probably found sources for Vanadyl
just started taking it yesterday. I got mine from "The
locally. I think I paid about $8-9 including tax.
Hope this is
helpful. I got it because I have been looking into help for
Candida. The first thing on the list of changes is stop
sugars and I
have a huge sugar craving and can't seem to stop it on my own. The
sales guy at the store started to steer me toward chromium picolate
and/or cinnamon but I've tried both and neither stops my craving for
sweets. I've have high blood sugar many times over the past 2
now I'm trying to change my diet. He said that this is
people with type 2 diabetes and I was heading in that direction so I'm
on day 2. I actually have candy and sweets in my drawer here
and yet I'm not interested in eating any of it. So this may
working. We shall see the longer time goes by.
Good luck with that, Jules. I know how hard it can be to
resist the sweets. It may help you to also eat some of the
rich in Vanadium, toward the top of this page. I've been
eating a lot of those foods and have noticed my cravings for simple
sugar has dropped significantly.
rocksteady - Saturday,
September 12, 2009 at 4:59 PM
I've been buying Vanadium with chromium from Vitacost.com.
It's about $15.00 for 180 pills. I take 1, twice daily with
food. Fasting blood sugar level has dropped significantly in
5 weeks, from 150-170 to 119-125.
Glad to see you are having good results. That's a cheap
supplement. Any idea how your triglycerides are or if they
changed? The study cited earlier on this page shows that
triglycerides can go up when taking Vanadyl Sulfate. I wonder
Vanadium with chromium has a different effect.
rocksteady - Saturday,
September 12, 2009 at 5:48 PM
I will let you know. My doctor has asked me to wait until
November to have my blood work done, which will cover hemoglobin and
lipid panel. Thanks for an informative website and your kind
In a couple months if you get your blood work done, that would
great if you remember to share your results with us. Thank
- Wednesday, September 30, 2009 at 05:43
I take vanadyl sulfate 2x a day from life extension my hba1c was 7.6
and now is 6.6 after 3mnths . I take 7.5 mg providing 1.5 vanadium . I
also take six flavor tea pills .
rocksteady - Thursday,
November 19, 2009 at 22:47
Well I had my blood panel done. My HGA1c is 7.0 after taking
the vanadium sulfate with chromium twice daily for 3 months
now. I'm really pleased with the results. Also, I lost 8
pounds. Not significant, but it's a start.
Wow, that sounds impressive to me. Glad to see your update!
- Saturday, January 2, 2010
Besides Vanadium, you can also use KOREAN GINSENG, and Cinnamon to help
control blood sugar, all three together have been reported to greatly
control type 2
- Saturday, January 23, 2010
Greetings to All,
Do I have to go off all prescriptions meds to see results from
Sev - Wednesday,
March 31, 2010
Those interested in Vanadium, here is a website for a vanadium all
I checked out the link above for the drink. I'm not sure how
it could be considered "all natural". It's water with an the
element Vanadium added. I don't think they found this water
naturally from a spring and bottled it, but it looks like they are
adding the element directly to the water. They recommend
it 30 minutes before each meal.
In my opinion, it seems
like a waste, encouraging people to add more empty bottles to the land
fills. Why not just take a pill containing the same Vanadium
Vanadyl) with a glass of clean water from home?
Islam Gapurov - Monday,
April 5, 2010
Let me answer your questions.
First of all thank you for visiting our web site http://www.aboutvanadis.com
1. Our water with vanadium comes out of underground water sources
inside of Japan, you may search on web about japanese vanadium water.
2. We add vitamins and sweetener, more detailed information you can
read here http://www.aboutvanadis.com/en/desc/vanadis/
3. Our bottles are made with recycled aluminum, which can be recycled
again for another purpose.
Should you have any questions please do not hesitate to contact me
fred - Thursday,
July 15, 2010
I have been taking vanadyl sulfate 10 mg./day to control sugar,
recently I sent for the item from Swanson on line and
vanadium 5 Mg. Is taking two of these the same?
Friday, August 20, 2010
I'M STARTING TONIGHT ON VANADYL. I ALSO TAKE VICTOZA WITH
METFORMAIN TWICE A DAY. WELL LET EVERYONE KNOW HOW IT WORKS.
henri - September
I would like to know why vanadyl sulfate makes my sugar
levels go up. I stayed on it for a month. could not stay on it
October 23, 2010
according to the stedmans medical dictionary Vanadayl sulfate lowers
LDL and assist in bone formation
Islam Gapurov -
April 26, 2011
The safe level of vanadium is not over 500 mcg a day.
Well, thanks for the tip. Without citing your source of info
on the safe level, I'm not sure I could accept that.
Islam Gapurov -
April 27, 2011
The Food and Nutrition Board, Institute of Medicine (2001),
has established a tolerable upper intake level (UL) of 1.8 mg/day
of elemental vanadium for adults aged 19 years,
based on a
lowest-observed-adverse-effects level (LOAEL) of 7.7 mg/kg/day and an
uncertainty factor of 300.
Kitty - May
I began taking Vanadyl,(with chromium & niacin for increased
assimulation), on March 8th, 2011. It will be two months on Mother's
Day. My fasting blood sugar has dropped from 134 to consistently being
90-107 every morning. My doctor is talking about weening me from the
needle twice a day to the pill, and then off insulin completely. I
still need to lose more weight, but now I feel so much hope. Also to
Sandra who used to buy her Vanadyl from Olympian Labs... This is where
I get mine from. They do still sell it. I purchase mine from Mia's, (a
local health food store for $10.99/ 100-capsule bottle).
May 10, 2011
Kitty, Thanks for your post. I read about Vanadyl in Dr
Colbert's book, "What you don't know may be killing you"
(sp?). He is pretty thorough man and I don't
would suggest anything that would be potentially damaging. I
suprised through online research that type 1 diabeties is actually an
autoimmune disease. Have been doing much research and am
to see that my pcos, prediabeties, gluten intolerance and Hashimoto's
thyroiditis are all related. Am on small (15) trial
Amour Thyroid, and am looking to address most of this problem through
natural means. It seems to me that many doctors
monitor patients on metformin for b12 absorbsion problems, and this
cause a domino affect of health crisis, if gone unchecked. Am
glad to hear that Vanadyl is working. No problems with
Triglicerides? Mine are high already, will have to monitor
Monohydrate - what it's good for and how to use
- Is It Good for You?
to Relieve a Sore Throat?